Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391774 | 0.84 | ALDH1A1 (0.37) | ALDH1A1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL31169778 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4564864 | 0.79 | KDM4E (0.49) | ALDH1A1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10612608 | 0.78 | NPC1 (0.33) | ALDH1A1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7426536 | 0.77 | TAAR1 (0.38) | ALDH1A1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29003727 | 0.77 | FFAR2 (0.42) | ALDH1A1KDM4EADRA2AADRA2C | |
| SCHEMBL2837058 | 0.76 | TAAR1 (0.42) | ALDH1A1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3684538 | 0.76 | ALDH1A1 (0.38) | ALDH1A1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1853863 | 0.75 | LMNA (0.38) | ALDH1A1KDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2424191 | 0.75 | PAX8 (0.35) | ALDH1A1KDM4ESMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3220910-A1 | AMINOPYRAZINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | Merck Sharp & Dohme Corp. (US) | 2017-09-27 | — | — | EP | disclosed |
| WO-2016081290-A1 | AMINOPYRAZINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME CORP. (US) | 2016-05-26 | — | — | WO | disclosed |
| WO-2012088124-A2 | TETRAHYDRO-AZACARBOLINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USES THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-06-28 | — | — | WO | disclosed |
| EP-0244177-B1 | Method for processing light-sensitive silver halide color photographic material | KONISHIROKU PHOTO IND (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0296854-B1 | METHOD FOR PROCESSING LIGHT-SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | KONICA CORPORATION (JP) | 1993-08-18 | — | — | EP | disclosed |
| EP-0168263-B1 | METHOD FOR PROCESSING LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL | KONICA CORPORATION (JP) | 1991-04-10 | — | — | EP | disclosed |
| EP-0217643-B1 | METHOD FOR PROCESSING LIGHT-SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | KONICA CORPORATION (JP) | 1991-01-23 | — | — | EP | disclosed |
| US-4983503-A | BLEACH-FIXING | KONICA CORPORATION (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0199604-B1 | PROCESSING METHOD FOR LIGHT-SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | KONICA CORPORATION (JP) | 1990-12-27 | — | — | EP | disclosed |
| US-4914008-A | Bleach fixing after color development | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0337560-A2 | 2-Phenylsulfinyl-nitro-pyridines, process for their preparation and their use | BAYER AG (DE) | 1989-10-18 | — | — | EP | disclosed |
| EP-0336186-A2 | Derivatives of triazolylmethylcyclopropyl-carbinols as material protecting agents | BAYER AG (DE) | 1989-10-11 | — | — | EP | disclosed |
| EP-0298338-A1 | Microbicidal agents | BAYER AG (DE) | 1989-01-11 | — | — | EP | disclosed |
| EP-0296854-A2 | Method for processing light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1988-12-28 | — | — | EP | disclosed |
| US-4778743-A | ALDEHYDE DERIVATIVE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| US-4778748-A | Method for processing light-sensitive silver halide color photographic material | KONISHIROKU PHOTO INDUSTRIES, CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0244177-A2 | Method for processing light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1987-11-04 | — | — | EP | disclosed |
| EP-0217643-A2 | Method for processing light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1987-04-08 | — | — | EP | disclosed |
| EP-0199604-A2 | Processing method for light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1986-10-29 | — | — | EP | disclosed |