Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201354 | 0.86 | DHODH (0.51) | DHODHL3MBTL1TDP1ALDH1A1ENPP3 | |
| SCHEMBL9440823 | 0.78 | MEN1 (0.59) | DHODHL3MBTL1ALDH1A1ENPP3ENPP1 | |
| SCHEMBL9440525 | 0.78 | SIRT2 (0.47) | L3MBTL1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL2756582 | 0.77 | LTA4H (0.45) | ENPP3ADRB1ADRB3LTA4HS1PR1 | |
| SCHEMBL18581467 | 0.76 | ADRB1 (0.49) | DHODHENPP3ENPP1ADRB1ADRB3 | |
| SCHEMBL9440941 | 0.74 | SIRT2 (0.56) | ALDH1A1NPSR1LTA4HS1PR1S1PR3 | |
| SCHEMBL9440535 | 0.74 | LTA4H (0.43) | L3MBTL1TDP1ALDH1A1ENPP3ENPP1 | |
| SCHEMBL12064926 | 0.74 | DAGLA (0.56) | L3MBTL1TDP1ALDH1A1ENPP3ENPP1 | |
| SCHEMBL9441048 | 0.74 | SIRT2 (0.63) | L3MBTL1TDP1ALDH1A1HPGDLTA4H | |
| SCHEMBL2707290 | 0.73 | ENPP3 (0.53) | DHODHL3MBTL1TDP1ALDH1A1ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371098-A | Use of oxazole compounds to treat osteoporosis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5239080-A | Oxazole compounds and their use as antidiabetic and bone-reduction inhibitory agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0440183-A1 | Oxazole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-07 | — | — | EP | disclosed |