Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.73 |
| ▸ | CNR1 | P21554 | 6/20 | 0.63 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6344128 | 0.83 | PTPN1 (0.53) | CNR2CNR1ESR1ESR2MAOB | |
| SCHEMBL20306409 | 0.81 | CNR2 (0.60) | CNR2CNR1EYA3SLC22A12ESR1 | |
| SCHEMBL9486239 | 0.77 | CNR2 (0.46) | CNR2CNR1EYA3SLC22A12ESR1 | |
| SCHEMBL6592398 | 0.76 | CNR1 (0.70) | CNR2CNR1ESR1ESR2 | |
| SCHEMBL11555382 | 0.75 | CNR2 (0.56) | CNR2CNR1EYA3SLC22A12ESR1 | |
| SCHEMBL11552702 | 0.75 | CNR1 (0.64) | CNR2CNR1ESR1ESR2 | |
| SCHEMBL11560954 | 0.74 | CNR2 (0.55) | CNR2CNR1 | |
| SCHEMBL6597362 | 0.74 | CNR2 (0.56) | CNR2CNR1ESR1ESR2 | |
| SCHEMBL11553455 | 0.73 | CNR1 (0.68) | CNR2CNR1ESR1ESR2 | |
| SCHEMBL11560887 | 0.72 | CNR2 (0.53) | CNR2CNR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5274000-A | 2-alkyl-3-carboxyalkylene or amidoalkyleneoxy-1,4-phenylene | KOTOBUKI SEIYAKU COMPANY LIMITED (JP) | 1993-12-28 | — | — | US | disclosed |
| US-5175184-A | Diuretics | KOTOBUKI SEIYAKU COMPANY LIMITED (JP) | 1992-12-29 | — | — | US | disclosed |
| US-5004750-A | Diuretics | KOTOBUKI SEIYAKU COMPANY LIMITED (JP) | 1991-04-02 | — | — | US | disclosed |
| US-4797415-A | DIURETICS FOR GOUT | KOTOBUKI SEIYAKU COMPANY LIMITED (JP) | 1989-01-10 | — | — | US | disclosed |