Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | GGH | Q92820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721691 | 0.75 | CYP2D6 (0.48) | LMNAKMT2ATDP1BLMTSHR | |
| SCHEMBL7721748 | 0.75 | LMNA (0.64) | LMNAKMT2ATDP1TSHRHSD17B10 | |
| SCHEMBL9445908 | 0.74 | FOLH1 (0.42) | LMNAKMT2ATDP1BLMTSHR | |
| SCHEMBL5566705 | 0.74 | TSHR (0.54) | LMNAKMT2ATDP1BLMTSHR | |
| SCHEMBL7720625 | 0.74 | CYP2D6 (0.46) | LMNAKMT2ATDP1BLMTSHR | |
| Medronic Acid SCHEMBL7764860 | 0.73 | KDM4E (0.48) | LMNAKMT2ATDP1BLMTSHR | |
| SCHEMBL2185204 | 0.72 | TSHR (0.52) | LMNAKMT2ATDP1TSHRHSD17B10 | |
| SCHEMBL1251621 | 0.72 | LMNA (0.41) | LMNAKMT2ATDP1BLMTSHR | |
| SCHEMBL7719757 | 0.71 | BHMT (0.49) | LMNAKMT2ATDP1TSHRHSD17B10 | |
| SCHEMBL9445930 | 0.69 | S1PR2 (0.52) | LMNABLMFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |