Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | PPID | Q08752 | 3/20 | 0.38 |
| ▸ | PPIB | P23284 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | PPIG | Q13427 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445917 | 0.87 | HDAC1 (0.41) | HDAC1PPIDSMN1; SMN2CCNT1CDK9 | |
| SCHEMBL22046625 | 0.82 | CYP4F2 (0.51) | LMNAHDAC1NPY5RSMN1; SMN2CCNT1 | |
| SCHEMBL9445924 | 0.81 | TSHR (0.46) | HPGDLMNAPPIDCCNT1CDK9 | |
| SCHEMBL3375825 | 0.78 | TSHR (0.50) | HDAC1NPY5RCCNT1CDK9EGFR | |
| SCHEMBL73418 | 0.76 | LOXL2 (0.53) | HPGDLMNAHDAC1SMN1; SMN2KDM4E | |
| SCHEMBL15062768 | 0.75 | CYP4F2 (0.46) | HPGDLMNASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL6811685 | 0.75 | KMT2A (0.50) | HPGDLMNAHDAC1SMN1; SMN2KDM4E | |
| SCHEMBL1279312 | 0.75 | CA1 (0.49) | HPGDLMNASMN1; SMN2KDM4ECA12 | |
| SCHEMBL23822678 | 0.74 | TSHR (0.43) | HDAC1NPY5RCCNT1CDK9EGFR | |
| SCHEMBL5004061 | 0.73 | ALDH1A1 (0.54) | HPGDLMNASMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |