SCHEMBL22046625

SCHEMBL22046625

CCOP(=O)(Cc1ccc(CC(=O)OC)cc1)OCC

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CYP4F2 P78329 1/20 0.51
▸ CYP4A11 Q02928 1/20 0.51
▸ SMN1; SMN2 Q16637 5/20 0.43
▸ ALDH1A1 P00352 5/20 0.43
▸ NPC1 O15118 4/20 0.43
▸ RAB9A P51151 4/20 0.43
▸ TP53 P04637 2/20 0.43
▸ LMNA P02545 2/20 0.43
▸ MAPT P10636 2/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ GFER P55789 1/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ HSP90AB1 P08238 1/20 0.42
▸ NPY5R Q15761 1/20 0.41
▸ HDAC1 Q13547 1/20 0.41
▸ CCNT1 O60563 1/20 0.40
▸ CDK9 P50750 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9433741 0.83 ALDH1A1 (0.47) ALDH1A1LMNAMAPTGAAKDM4E
SCHEMBL3375825 0.82 TSHR (0.50) TP53MAPTNPY5RHDAC1CCNT1
SCHEMBL9445980 0.82 HPGD (0.39) SMN1; SMN2ALDH1A1NPC1RAB9ALMNA
SCHEMBL73418 0.81 LOXL2 (0.53) CYP4F2CYP4A11SMN1; SMN2ALDH1A1NPC1
SCHEMBL27706566 0.79 ABCC4 (0.51) ALDH1A1LMNAGAANPY5RHDAC1
SCHEMBL23822678 0.79 TSHR (0.43) MAPTNPY5RHDAC1CCNT1CDK9
SCHEMBL4113212 0.78 CYP4F2 (0.76) CYP4F2CYP4A11SMN1; SMN2ALDH1A1NPC1
SCHEMBL13981237 0.78 ENPP2 (0.51) MAPTNPY5RHDAC1CCNT1CDK9
SCHEMBL9512480 0.78 PPARD (0.45) MAPTNPY5RHDAC1CCNT1CDK9
SCHEMBL283016 0.78 EGFR (0.47) ALDH1A1TP53LMNAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. (US) 2023-11-21 — — US disclosed
US-11237170-B2 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. (US) 2022-02-01 — — US disclosed
US-20200378975-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION AAT BIOQUEST, INC. (US) 2020-12-03 — — US disclosed
US-20200174006-A1 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. 2020-06-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS CYP4F2 1989/4885CYP4A11 247/4885SMN1; SMN2 2937/4885
US-20200174006-A1 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS CYP4F2 1989/4885CYP4A11 247/4885SMN1; SMN2 2937/4885
US-11237170-B2 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS CYP4F2 1989/4885CYP4A11 247/4885SMN1; SMN2 2937/4885
US-20200378975-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION STUB1, SPR, HLCS CYP4F2 1989/4885CYP4A11 247/4885SMN1; SMN2 2937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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