SCHEMBL9446563

SCHEMBL9446563

CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FPR1 P21462 4/20 0.63
FPR2 P25090 4/20 0.63
CAPN1 P07384 2/20 0.52
MMP3 P08254 9/20 0.51
MMP2 P08253 6/20 0.49
MMP1 P03956 2/20 0.48
MMP9 P14780 1/20 0.48
CTSB P07858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9446555 1.00 FPR1 (0.63) FPR1FPR2CAPN1MMP3MMP2
SCHEMBL3239797 0.86 FPR1 (0.51) FPR1FPR2MMP1
SCHEMBL23616375 0.85 MMP3 (0.66) CAPN1MMP3MMP2MMP1
N-Formylmethionyl-Leucylphenylalanine SCHEMBL39528 0.85 FPR1 (0.61) FPR1FPR2MMP2MMP9
N-Formylmethionyl-Leucylphenylalanine SCHEMBL17202476 0.85 FPR1 (0.61) FPR1FPR2MMP2MMP9
N-Formylmethionyl-Leucylphenylalanine SCHEMBL4969844 0.85 FPR1 (0.61) FPR1FPR2MMP2MMP9
N-Formylmethionyl-Leucylphenylalanine SCHEMBL4592799 0.85 FPR1 (0.61) FPR1FPR2MMP2MMP9
N-Formylmethionyl-Leucylphenylalanine SCHEMBL39529 0.85 FPR1 (0.61) FPR1FPR2MMP2MMP9
N-Formylmethionyl-Leucylphenylalanine SCHEMBL9903983 0.85 FPR1 (0.61) FPR1FPR2MMP2MMP9
N-Formylmethionyl-Leucylphenylalanine SCHEMBL7127847 0.85 FPR1 (0.61) FPR1FPR2MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4393507-A1 PHARMACEUTICAL COMPOSITION FOR TREATING PERIPHERAL NERVE INJURY National University Corporation Hokkaido University (JP) 2024-07-03 EP disclosed
WO-2023007779-A1 PHARMACEUTICAL COMPOSITION FOR TREATING PERIPHERAL NERVE INJURY 国立大学法人北海道大学 2023-02-02 WO disclosed
US-5262406-A Preventing transfer of infection from mother to fetus, treating newborns MED-TAL, INC. (US) 1993-11-16 US disclosed
US-5135922-A Treatment of opportunistic infections in AIDS patients MED-TAL, INC. (US) 1992-08-04 US disclosed
EP-0477270-A1 PREVENTION AND TREATMENT OF MICROBIAL INFECTION BY PHOSPHOGLYCERIDES MED-TAL, INC. (US) 1992-04-01 EP disclosed
WO-1990015609-A1 PREVENTION AND TREATMENT OF MICROBIAL INFECTION BY PHOSPHOGLYCERIDES MED-TAL, INC. (US) 1990-12-27 WO disclosed