Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801508 | 0.77 | PGR (0.91) | PGRFFAR1ARMAPTNPSR1 | |
| SCHEMBL8066981 | 0.75 | LMNA (0.82) | LMNAL3MBTL1MAPT | |
| SCHEMBL9800673 | 0.74 | PGR (0.56) | PGRLMNAL3MBTL1FFAR1AR | |
| SCHEMBL5230154 | 0.73 | PGR (0.69) | PGRLMNAFFAR1ARMAPT | |
| SCHEMBL9800660 | 0.72 | CKS1B (0.58) | PGRLMNAL3MBTL1FFAR1MAPT | |
| SCHEMBL9446952 | 0.72 | PGR (0.54) | PGRLMNAL3MBTL1FFAR1AR | |
| SCHEMBL7518591 | 0.72 | GRIN1 (0.75) | PGRFFAR1AR | |
| SCHEMBL9446946 | 0.71 | PGR (0.62) | PGRLMNAL3MBTL1ARMAPT | |
| SCHEMBL9447120 | 0.71 | PGR (0.62) | PGRLMNAL3MBTL1ARMAPT | |
| SCHEMBL7584032 | 0.71 | CES1 (0.81) | PGRARCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |