Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446946 | 0.80 | PGR (0.62) | PGRCES1ALDH1A1KMT2APOLB | |
| SCHEMBL9800630 | 0.80 | PGR (0.64) | PGRKMT2ATSHRAR | |
| SCHEMBL9446952 | 0.79 | PGR (0.54) | PGRCES1FFAR1ALDH1A1KMT2A | |
| SCHEMBL9447120 | 0.78 | PGR (0.62) | PGRCES1ALDH1A1KMT2APOLB | |
| SCHEMBL9800660 | 0.74 | CKS1B (0.58) | PGRFFAR1ALDH1A1KMT2APOLB | |
| SCHEMBL9446971 | 0.74 | PGR (0.62) | PGRCES1FFAR1L3MBTL1LMNA | |
| SCHEMBL4696274 | 0.72 | PPARG (0.72) | PGRCES1ALDH1A1MAPTNPSR1 | |
| SCHEMBL5801508 | 0.71 | PGR (0.91) | PGRCES1FFAR1ALDH1A1KMT2A | |
| SCHEMBL9800661 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL9800651 | 0.70 | HTT (0.49) | ALDH1A1KMT2AL3MBTL1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |