Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.47 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.44 |
| ▸ | CCR8 | P51685 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446967 | 0.81 | CCR1 (0.50) | PSMD14COPS5CCR1CCR5CCR8 | |
| SCHEMBL9446957 | 0.80 | MEN1 (0.48) | PSMD14COPS5MEN1KMT2AALDH1A1 | |
| SCHEMBL1337689 | 0.76 | HTR1A (0.61) | PSMD14COPS5CCR1CCR5CCR8 | |
| SCHEMBL9447019 | 0.75 | KDM4E (0.57) | MEN1KMT2AAPAF1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16620693 | 0.73 | KDM4E (0.52) | MEN1KMT2AAPAF1ALDH1A1L3MBTL1 | |
| SCHEMBL26073093 | 0.73 | PSMD14 (0.54) | PSMD14COPS5CCR1CCR5CCR8 | |
| SCHEMBL29035107 | 0.73 | PSMD14 (0.54) | PSMD14COPS5CCR1CCR5CCR8 | |
| SCHEMBL5239727 | 0.73 | PSMD14 (0.59) | PSMD14COPS5CCR1CCR5CCR8 | |
| SCHEMBL30423646 | 0.73 | PSMD14 (0.54) | PSMD14COPS5CCR1CCR5CCR8 | |
| SCHEMBL30644899 | 0.73 | ALDH1A1 (0.56) | MEN1KMT2AAPAF1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |