Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448358 | 0.86 | MAPT (0.57) | NPC1RAB9AALDH1A1HTTMAPT | |
| SCHEMBL2583947 | 0.77 | KMT2A (0.55) | NPC1RAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL18893559 | 0.75 | MEN1 (0.54) | MEN1KMT2AHTR7PARP1PARP10 | |
| SCHEMBL3989669 | 0.74 | L3MBTL1 (0.52) | NPC1RAB9AALDH1A1MAPTGAA | |
| SCHEMBL8686789 | 0.73 | HTR7 (0.55) | MEN1KMT2AHTR7HDAC1HDAC8 | |
| SCHEMBL8686770 | 0.73 | HTR7 (0.55) | MEN1KMT2AHTR7HDAC1HDAC8 | |
| SCHEMBL19710767 | 0.73 | HTR7 (0.55) | RAB9AGAALMNAMEN1KMT2A | |
| SCHEMBL9448456 | 0.71 | PARP1 (0.51) | ALDH1A1MAPTMEN1KMT2AHTR7 | |
| SCHEMBL11935020 | 0.71 | HTR7 (0.54) | MEN1KMT2AHTR7HDAC1HDAC8 | |
| SCHEMBL461708 | 0.71 | HTR7 (0.54) | GAAMEN1KMT2AHTR7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215738-A | Used for destroying hypoxic tumor cells | SRI INTERNATIONAL (US) | 1993-06-01 | — | — | US | disclosed |