Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448971 | 0.82 | OPRM1 (0.51) | ALDH1A1MAPTHTR6MCHR1OPRM1 | |
| SCHEMBL9448889 | 0.82 | SLC6A4 (0.46) | HTR6TLR9TLR8TLR7MCHR1 | |
| SCHEMBL9449066 | 0.82 | CYP1A2 (0.40) | GAAHSD17B10HTR6TLR9TLR8 | |
| SCHEMBL9448767 | 0.81 | MCHR1 (0.50) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL9448855 | 0.80 | CHRNA7 (0.49) | GAAMCHR1CHRNA7CHRM2CHRM4 | |
| SCHEMBL9448816 | 0.80 | MCHR1 (0.51) | MCHR1 | |
| SCHEMBL9448822 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL9449116 | 0.77 | KMT2A (0.41) | ALDH1A1GAATSHRMCHR1CHRNA7 | |
| SCHEMBL9449189 | 0.77 | MCHR1 (0.40) | KDM4EALDH1A1HPGDHSD17B10HTR6 | |
| SCHEMBL9449057 | 0.77 | NOS3 (0.50) | KDM4EHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227386-A | INDOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-07-13 | — | — | US | disclosed |