Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.36 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.36 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449042 | 0.91 | HPGD (0.35) | MCHR1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9448767 | 0.86 | MCHR1 (0.50) | MCHR1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9449097 | 0.83 | LMNA (0.40) | MCHR1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9448822 | 0.83 | KDM4E (0.47) | MCHR1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9448904 | 0.81 | KDM4E (0.41) | MCHR1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9449136 | 0.81 | LMNA (0.38) | MCHR1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9448869 | 0.81 | MAPKAPK2 (0.41) | MCHR1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9448900 | 0.80 | MAPKAPK2 (0.40) | MCHR1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9449214 | 0.80 | NOS3 (0.46) | HTR2CHTR7HTR6 | |
| SCHEMBL9449668 | 0.79 | TRPM8 (0.51) | HSD17B10KDM4EHPGDMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227386-A | INDOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-07-13 | — | — | US | disclosed |