Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448924 | 0.87 | KDM4E (0.40) | KMT2ACHRNA7CHRM2CHRM4CHRM5 | |
| SCHEMBL9449052 | 0.85 | KDM4E (0.43) | KMT2ACHRNA7HTR3AMCHR1ALDH1A1 | |
| SCHEMBL9448855 | 0.85 | CHRNA7 (0.49) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9449042 | 0.81 | HPGD (0.35) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9448852 | 0.80 | ALDH1A1 (0.40) | CHRNA7HTR3AALOX15CHRM2CHRM4 | |
| SCHEMBL9448864 | 0.80 | GAA (0.47) | KMT2ACHRNA7HTR3ACHRM2CHRM1 | |
| SCHEMBL9449046 | 0.80 | KMT2A (0.36) | KMT2AALOX15ALDH1A1HTTGAA | |
| SCHEMBL9449289 | 0.79 | KMT2A (0.38) | KMT2AALOX15ALDH1A1HTTGAA | |
| SCHEMBL9448889 | 0.79 | SLC6A4 (0.46) | KIF11CHRNA7HTR3ACHRM2CHRM4 | |
| SCHEMBL9448971 | 0.79 | OPRM1 (0.51) | KMT2AHTR3AMCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227386-A | INDOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-07-13 | — | — | US | disclosed |