Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF20A | O95235 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128717 | 0.86 | KIF20A (0.58) | KIF20ACYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL10806187 | 0.85 | CYP19A1 (0.51) | KIF20ACYP19A1CYP3A4CYP2D6ESR1 | |
| SCHEMBL9451727 | 0.85 | KIF20A (0.51) | KIF20ACYP19A1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL16432269 | 0.85 | KIF20A (0.51) | KIF20ACYP19A1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL19069229 | 0.85 | KIF20A (0.51) | KIF20ACYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL17455083 | 0.85 | CYP3A4 (0.60) | KIF20ACYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL9696882 | 0.82 | KIF20A (0.48) | KIF20ACYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL9312100 | 0.82 | KIF20A (0.48) | KIF20ACYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL5054960 | 0.81 | ESR2 (0.56) | CYP3A4SLC6A2SLC6A4SLC6A3ESR1 | |
| SCHEMBL10372046 | 0.80 | CYP3A4 (0.43) | KIF20ACYP19A1CYP3A4CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171442-A1 | PROCESS FOR THE PREPARATION OF BACLOFEN AND ITS INTERMEDIATE | PIRAMAL PHARMA LIMITED (IN) | 2021-06-10 | — | — | US | disclosed |
| US-20210171442-A1 | PROCESS FOR THE PREPARATION OF BACLOFEN AND ITS INTERMEDIATE | PIRAMAL PHARMA LIMITED (IN) | 2021-06-10 | — | — | US | disclosed |
| US-20180208544-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BACLOFEN AND ITS INTERMEDIATE | Piramal Enterprises Limited (IN) | 2018-07-26 | — | — | US | disclosed |
| US-20180208544-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BACLOFEN AND ITS INTERMEDIATE | Piramal Enterprises Limited (IN) | 2018-07-26 | — | — | US | disclosed |
| US-20180208544-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BACLOFEN AND ITS INTERMEDIATE | Piramal Enterprises Limited (IN) | 2018-07-26 | — | — | US | disclosed |
| EP-3322691-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BACLOFEN AND ITS INTERMEDIATE | Piramal Enterprises Limited (IN) | 2018-05-23 | — | — | EP | disclosed |
| WO-2017009753-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BACLOFEN AND ITS INTERMEDIATE | Piramal Enterprises Limited (IN) | 2017-01-19 | — | — | WO | disclosed |
| US-5240925-A | FUNGICIDAL 2-ARYL-2-CYANO-2-(HETEROCYCLYLALKYL)ETHYL-1,2,4-TRIAZOLES | ROHM AND HAAS COMPANY (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0529973-A1 | Fungicidal 2-aryl-2-cyano-2-(heterocyclylalkyl)ethyl-1,2,4-triazoles | ROHM AND HAAS COMPANY (US) | 1993-03-03 | — | — | EP | disclosed |
| EP-0214793-B1 | (2-CYANO-2-ARYLETHYL)PYRIDINES, THEIR PREPARATION AND USE AS FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |
| US-4933339-A | PHYTOPATHOGENS | ROHM AND HAAS COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0214793-A1 | (2-Cyano-2-arylethyl)pyridines, their preparation and use as fungicides | ROHM AND HAAS COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208544-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BACLOFEN AND ITS INTERMEDIATE | SLC6A13, SLC6A1, SLC6A11 | KIF20A 2226/4885CYP19A1 1868/4885CYP3A4 174/4885 |
| US-20210171442-A1 | PROCESS FOR THE PREPARATION OF BACLOFEN AND ITS INTERMEDIATE | SLC6A13, GRHPR, SLC6A1 | KIF20A 2664/4885CYP19A1 1773/4885CYP3A4 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.