Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL10002813 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL318366 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL15769141 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL514605 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL57827 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL301207 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL637278 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL4960168 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL94686 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL6720430 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116943-A1 | TETRAHYDROBENZOFURODIAZEPINONE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2024-04-11 | — | — | US | disclosed |
| WO-2023163140-A1 | INDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | 日本たばこ産業株式会社 | 2023-08-31 | — | — | WO | disclosed |
| EP-4227308-A1 | TETRAHYDROBENZOFURODIAZEPINONE COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | Japan Tobacco Inc. (JP) | 2023-08-16 | — | — | EP | disclosed |
| CN-116437927-A | Tetrahydrobenzodiazepine ketone compound and pharmaceutical application thereof | 日本烟草产业株式会社 | 2023-07-14 | — | — | CN | disclosed |
| US-11643417-B2 | Tetrahydrobenzofurodiazepinone compound and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2023-05-09 | — | — | US | disclosed |
| US-20220162220-A1 | TETRAHYDROBENZOFURODIAZEPINONE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2022-05-26 | — | — | US | disclosed |
| US-20210238136-A1 | AZETIDINE DERIVATIVE, AND PRODRUG THEREOF | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-08-05 | — | — | US | disclosed |
| EP-3805203-A1 | AZETIDINE DERIVATIVE, AND PRODRUG THEREOF | Daiichi Sankyo Company, Limited (JP) | 2021-04-14 | — | — | EP | disclosed |
| EP-2871178-B1 | CATIONIC LIPID | KYOWA KIRIN CO LTD (JP) | 2020-12-23 | — | — | EP | disclosed |
| CN-104640847-B | Novel Renin Inhibitors | 上海医药集团股份有限公司 | 2019-10-15 | — | — | CN | disclosed |
| US-20120065231-A1 | THIOPHENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
| EP-2426117-A1 | THIOPHENE DERIVATIVE | Sumitomo Chemical Company, Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-7022310-B2 | Stable isotope-labeled amino acid and method for incorporating same into target protein | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2006-04-04 | — | — | US | disclosed |
| US-20050084452-A1 | Stable isotope-labeled amino acid and method for incorporating same into target protein | JAPANESE SCIENCE AND TECHNOLOGY AGENCY | 2005-04-21 | — | — | US | disclosed |
| EP-0807675-B1 | Optically active compound, liquid crystal compositions containing the optically active compound, and liquid crystal display device | MITSUBISHI GAS CHEMICAL CO (JP) | 2001-08-22 | — | — | EP | disclosed |
| EP-0844294-B1 | Racemic compound and anti-ferroelectric liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-5985172-A | LARGE-SIZED LIQUID CRYSTAL DISPLAY DEVICE OF HIGHER PERFORMANCE THAT HAS A HIGHER DISPLAY CAPACITY AND A HIGHER DISPLAY QUALITY | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5840209-A | DRIVEN BY A VOLTAGE CARRIED OUT BY SWITCHING AMONG ONE ANTI-FERROELECTRIC STATE AND TWO FERRIELECTRIC STATES | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0844294-A1 | Racemic compound and anti-ferroelectric liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1998-05-27 | — | — | EP | disclosed |
| EP-0807675-A1 | Optically active compound, liquid crystal compositions containing the optically active compound, and liquid crystal display device | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1997-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065231-A1 | THIOPHENE DERIVATIVE | AR, NR5A1, SHBG | ALDH1A1 729/4885LMNA 4681/4885HSD17B10 126/4885 |
| US-20240116943-A1 | TETRAHYDROBENZOFURODIAZEPINONE COMPOUND AND PHARMACEUTICAL USE THEREOF | PIM1, PIM2, PIM3 | ALDH1A1 76/4885LMNA 3718/4885HSD17B10 906/4885 |
| US-11643417-B2 | Tetrahydrobenzofurodiazepinone compound and pharmaceutical use thereof | PIM1, PIM2, PIM3 | ALDH1A1 76/4885LMNA 3718/4885HSD17B10 906/4885 |
| US-20050084452-A1 | Stable isotope-labeled amino acid and method for incorporating same into target protein | GEMIN5, ATIC, AIP | ALDH1A1 4079/4885LMNA 3406/4885HSD17B10 2888/4885 |
| US-20220162220-A1 | TETRAHYDROBENZOFURODIAZEPINONE COMPOUND AND PHARMACEUTICAL USE THEREOF | PIM1, PIM2, PIM3 | ALDH1A1 76/4885LMNA 3718/4885HSD17B10 906/4885 |
| US-20210238136-A1 | AZETIDINE DERIVATIVE, AND PRODRUG THEREOF | IFNG, IFNAR1, TLR9 | ALDH1A1 1128/4885LMNA 2362/4885HSD17B10 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.