Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280301 | 0.86 | LTA4H (0.63) | LTA4HRORCKDM4EOPRM1 | |
| SCHEMBL25389253 | 0.82 | GPR119 (0.59) | — | |
| SCHEMBL18412166 | 0.81 | KDM4E (0.57) | LTA4HCYP2D6CHRM1HRH1HRH3 | |
| SCHEMBL13452623 | 0.80 | HRH3 (0.59) | LTA4HCYP2D6CHRM1HRH1HRH3 | |
| SCHEMBL9451538 | 0.80 | MAPT (0.48) | CYP2D6CHRM1HRH1KDM4EGAA | |
| SCHEMBL6538883 | 0.78 | NR1H4 (0.52) | OPRM1TMEM97 | |
| SCHEMBL14559864 | 0.78 | MEN1 (0.56) | KDM4EMAPTOPRM1 | |
| SCHEMBL26618018 | 0.78 | KMT2A (0.55) | LTA4HRORCTACR1OPRM1 | |
| SCHEMBL9451676 | 0.77 | USP2 (0.52) | LTA4HCYP2D6CHRM1HRH1KDM4E | |
| SCHEMBL6538705 | 0.76 | CCR5 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260318-A | Phenylpiperidylamines and drugs containing them | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |