Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9451973 | 0.77 | NPC1 (0.48) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9452018 | 0.77 | ROCK2 (0.44) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9451906 | 0.70 | MAPT (0.44) | MAPTALDH1A1KDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL9452019 | 0.70 | CYP1A1 (0.51) | MAPTALDH1A1KDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL10449029 | 0.70 | CYP1A1 (0.51) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9451909 | 0.69 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9452013 | 0.69 | PTGS2 (0.53) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL11562896 | 0.68 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9664437 | 0.67 | MAPT (0.43) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7279680 | 0.67 | ALDH1A1 (0.66) | MAPTALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229386-A | Anticoagulants, hypotensive agents, antiallergens, antiinflammatory agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-20 | — | — | US | disclosed |
| US-5145860-A | Anticoagulants, vasodilators, antiinflammatory, antiallergens, enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0388909-A2 | Thiazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |