Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710578 | 0.84 | COPS5 (0.38) | MAPTMEN1KMT2APOLBGAA | |
| SCHEMBL9457482 | 0.77 | POLB (0.50) | RAB9AMAPTMEN1KMT2APOLB | |
| SCHEMBL9710427 | 0.77 | RAB9A (0.44) | RAB9AIDO1MAPTMEN1KMT2A | |
| SCHEMBL9427047 | 0.76 | ALDH1A1 (0.50) | RAB9AMAPTMEN1KMT2APOLB | |
| SCHEMBL9458234 | 0.75 | MEN1 (0.43) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL9457588 | 0.71 | RAB9A (0.47) | RAB9AMAPTMEN1KMT2APOLB | |
| SCHEMBL4834573 | 0.71 | RAB9A (0.51) | RAB9AIDO1MAPTMEN1KMT2A | |
| SCHEMBL9710207 | 0.69 | COPS5 (0.36) | — | |
| SCHEMBL27410113 | 0.66 | TSHR (0.56) | IDO1MAPTMEN1KMT2AHTT | |
| SCHEMBL260345 | 0.64 | RAB9A (0.60) | RAB9AMAPTGAALMNAPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |