Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 10/20 | 0.45 |
| ▸ | XIAP | P98170 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9457392 | 0.84 | PLTP (0.42) | AOC3 | |
| SCHEMBL9458112 | 0.83 | AOC3 (0.58) | AOC3XIAP | |
| SCHEMBL9458174 | 0.83 | SMN1; SMN2 (0.42) | AOC3PTGS2COPS5 | |
| SCHEMBL9457466 | 0.77 | MAPT (0.42) | AOC3XIAP | |
| SCHEMBL9457422 | 0.76 | COPS5 (0.44) | COPS5 | |
| SCHEMBL9458127 | 0.74 | HTT (0.40) | AOC3COPS5 | |
| SCHEMBL9458088 | 0.74 | CYP3A4 (0.38) | AOC3COPS5 | |
| SCHEMBL4875662 | 0.74 | AOC3 (0.76) | AOC3XIAP | |
| SCHEMBL9710192 | 0.73 | LDHA (0.37) | AOC3COPS5 | |
| SCHEMBL9710207 | 0.72 | COPS5 (0.36) | AOC3COPS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192781-A | Cardiovascular | LABORATOIRES UPSA (FR) | 1993-03-09 | — | — | US | disclosed |