Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458070 | 0.83 | AOC3 (0.45) | PTGS2COPS5AOC3 | |
| SCHEMBL9457588 | 0.83 | RAB9A (0.47) | SMN1; SMN2LMNAHPGDMEN1KMT2A | |
| SCHEMBL9457501 | 0.73 | ALDH1A1 (0.45) | SMN1; SMN2MEN1KMT2ACOPS5RAB9A | |
| SCHEMBL9710578 | 0.69 | COPS5 (0.38) | LMNAHPGDMEN1KMT2ACOPS5 | |
| SCHEMBL31635693 | 0.68 | LMNA (0.50) | SMN1; SMN2LMNAHPGDMEN1KMT2A | |
| SCHEMBL9457392 | 0.68 | PLTP (0.42) | SMN1; SMN2LMNAMEN1KMT2ARAB9A | |
| SCHEMBL8977465 | 0.68 | NPC1 (0.54) | SMN1; SMN2LMNAHPGDMEN1KMT2A | |
| SCHEMBL24952924 | 0.68 | XIAP (0.56) | SMN1; SMN2LMNAHPGDMEN1KMT2A | |
| SCHEMBL4875662 | 0.65 | AOC3 (0.76) | AOC3 | |
| SCHEMBL9458112 | 0.65 | AOC3 (0.58) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192781-A | Cardiovascular | LABORATOIRES UPSA (FR) | 1993-03-09 | — | — | US | disclosed |