Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of 3-Methylbutanoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.41 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Methylbutanoic Acid SCHEMBL27465475 | 0.87 | SLC22A6 (0.50) | TDP1SLC22A6ALDH1A1SMN1; SMN2CACNA2D1 | |
| 3-Methylbutanoic Acid SCHEMBL1331498 | 0.86 | — | — | |
| 3-Methylbutanoic Acid SCHEMBL43436 | 0.86 | — | — | |
| 3-Methylbutanoic Acid SCHEMBL467274 | 0.86 | TDP1 (0.56) | TDP1SLC22A6ALDH1A1SMN1; SMN2CACNA2D1 | |
| 3-Methylbutanoic Acid SCHEMBL1373554 | 0.83 | TDP1 (0.48) | TDP1SLC22A6ALDH1A1SMN1; SMN2CACNA2D1 | |
| 3-Methylbutanoic Acid SCHEMBL6113289 | 0.83 | — | — | |
| 3-Methylbutanoic Acid SCHEMBL9185998 | 0.83 | — | — | |
| 3-Methylbutanoic Acid SCHEMBL6139482 | 0.83 | — | — | |
| 3-Methylbutanoic Acid SCHEMBL15772049 | 0.83 | — | — | |
| 3-Methylbutanoic Acid SCHEMBL8572477 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220323912-A1 | LIQUID PURIFICATION MEMBRANE INCLUDING CARBONACEOUS MATERIALS AND METHODS OF FORMING THEM | MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT | 2022-10-13 | — | — | US | claimed |
| EP-0907673-A4 | TWO-COMPONENT WATERBORNE POLYURETHANE COATING | ARCO CHEM TECH (US) | 1999-11-10 | — | — | EP | claimed |
| EP-0907673-A1 | TWO-COMPONENT WATERBORNE POLYURETHANE COATING | ARCO Chemical Technology, L.P. (US) | 1999-04-14 | — | — | EP | claimed |
| WO-1997045475-A1 | TWO-COMPONENT WATERBORNE POLYURETHANE COATING | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1997-12-04 | — | — | WO | claimed |
| US-20260125596-A1 | CURABLE COMPOSITION, CURED LAYER USING THE COMPOSITION AND DISPLAY DEVICE INCLUDING THE CURED LAYER | SAMSUNG SDI CO LTD (KR) | 2026-05-07 | — | — | US | disclosed |
| US-20260118551-A1 | CORE-SHELL COMPOUND, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME, PHOTOSENSITIVE RESIN LAYER, COLOR FILTER, AND CMOS IMAGE SENSOR | SMSUNG SDI CO LTD (KR) | 2026-04-30 | — | — | US | disclosed |
| US-12606650-B2 | Curable composition, cured film manufactured using composition, color filter including cured film, and display device including color filter | SAMSUNG SDI CO., LTD. (KR) | 2026-04-21 | — | — | US | disclosed |
| US-20260001971-A1 | CURABLE COMPOSITION, CURED LAYER USING THE COMPOSITION AND DISPLAY DEVICE INCLUDING THE CURED LAYER | SAMSUNG SDI CO LTD (KR) | 2026-01-01 | — | — | US | disclosed |
| US-20260003272-A1 | CURABLE COMPOSITION, CURED LAYER USING THE COMPOSITION, AND DISPLAY DEVICE INCLUDING THE CURED LAYER | SAMSUNG SDI CO LTD (KR) | 2026-01-01 | — | — | US | disclosed |
| US-20250326876-A1 | CURABLE COMPOSITION, CURED LAYER MANUFACTURED USING SAME COMPOSITION, COLOR FILTER INCLUDING SAME CURED LAYER, AND DISPLAY DEVICE INCLUDING SAME COLOR FILTER | SAMSUNG SDI CO LTD (KR) | 2025-10-23 | — | — | US | disclosed |
| US-20250304733-A1 | CURABLE COMPOSITION, CURED LAYER USING THE COMPOSITION, COLOR FILTER INCLUDING THE CURED LAYER AND DISPLAY DEVICE INCLUDING THE COLOR FILTER | SAMSUNG SDI CO., LTD. (KR) | 2025-10-02 | — | — | US | disclosed |
| US-12365833-B2 | Curable composition, cured film produced using same, and color filter comprising same | SAMSUNG SDI CO., LTD. (KR) | 2025-07-22 | — | — | US | disclosed |
| US-20100167188-A1 | Pigment Dispersion Composition, Resist Composition for Color Filter Including the Same, and Color Filter Using the Same | CHEIL INDUSTRIES INC. (KR) | 2010-07-01 | — | — | US | disclosed |
| WO-2010050650-A1 | PIGMENT DISPERSION COMPOSITION AND COLOR RESIST COMPOSITION INCLUDING THE SAME AND COLOR FILTER USING THE SAME | CHEIL INDUSTRIES INC. (KR) | 2010-05-06 | — | — | WO | disclosed |
| EP-1219662-B1 | POLYAMIC ACID ESTER | ASAHI CHEMICAL IND (JP) | 2004-08-04 | — | — | EP | disclosed |
| US-6692873-B1 | IMPROVING PRODUCTIVITY; EMPLOYING PROPYLENE GLYCOL METHYL ETHER ACETATE, PROPYLENE GLYCOL MONOMETHYL ETHER OR PROPYLENE GLYCOL MONOETHYL ETHER AS PLASTICIZER WHICH CAN BE REMOVED UNDER VACUUM ELIMINATING SOLVENT EXTRACTION | SKC CO., LTD. (KR) | 2004-02-17 | — | — | US | disclosed |
| EP-1219662-A1 | POLYAMIC ACID ESTER | Asahi Kasei Kabushiki Kaisha (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0907673-A4 | TWO-COMPONENT WATERBORNE POLYURETHANE COATING | ARCO CHEM TECH (US) | 1999-11-10 | — | — | EP | disclosed |
| EP-0907673-A1 | TWO-COMPONENT WATERBORNE POLYURETHANE COATING | ARCO Chemical Technology, L.P. (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997045475-A1 | TWO-COMPONENT WATERBORNE POLYURETHANE COATING | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1997-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12606650-B2 | Curable composition, cured film manufactured using composition, color filter including cured film, and display device including color filter | PRKD1, CRY2, PRKD2 | TDP1 3996/4885SLC22A6 3910/4885ALDH1A1 1717/4885 |
| US-20260001971-A1 | CURABLE COMPOSITION, CURED LAYER USING THE COMPOSITION AND DISPLAY DEVICE INCLUDING THE CURED LAYER | EPB41L2, CIB1, ILK | TDP1 3436/4885SLC22A6 4736/4885ALDH1A1 306/4885 |
| US-20260003272-A1 | CURABLE COMPOSITION, CURED LAYER USING THE COMPOSITION, AND DISPLAY DEVICE INCLUDING THE CURED LAYER | ILK, EPB41L2, LASP1 | TDP1 3940/4885SLC22A6 4781/4885ALDH1A1 261/4885 |
| US-20260118551-A1 | CORE-SHELL COMPOUND, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME, PHOTOSENSITIVE RESIN LAYER, COLOR FILTER, AND CMOS IMAGE SENSOR | RCOR1, TAS1R2, TAS1R1 | TDP1 4611/4885SLC22A6 3413/4885ALDH1A1 1597/4885 |
| US-20260125596-A1 | CURABLE COMPOSITION, CURED LAYER USING THE COMPOSITION AND DISPLAY DEVICE INCLUDING THE CURED LAYER | C5, CORO1C, CCT4 | TDP1 4102/4885SLC22A6 4582/4885ALDH1A1 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.