Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.86 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.86 |
| ▸ | PTGES | O14684 | 2/20 | 0.86 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.86 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203023 | 0.94 | ALOX5 (0.81) | ALOX5PTGS1PTGESALOX5APPTGS2 | |
| Licofelone SCHEMBL237833 | 0.93 | ALOX5 (1.00) | ALOX5PTGS1PTGESALOX5APPTGS2 | |
| SCHEMBL18782756 | 0.93 | ALOX5 (0.79) | ALOX5PTGS1PTGESALOX5APPTGS2 | |
| Licofelone SCHEMBL1843506 | 0.89 | PTGES (0.92) | ALOX5PTGS1PTGESALOX5APPTGS2 | |
| Licofelone SCHEMBL7737421 | 0.87 | PTGES (0.88) | ALOX5PTGS1PTGESALOX5APPTGS2 | |
| SCHEMBL4148447 | 0.85 | ALOX5 (1.00) | ALOX5PTGS1PTGESALOX5APPTGS2 | |
| Licofelone SCHEMBL1394262 | 0.85 | PTGES (0.84) | ALOX5PTGS1PTGESALOX5APPTGS2 | |
| Licofelone SCHEMBL1393673 | 0.84 | PTGES (0.83) | ALOX5PTGS1PTGESALOX5APPTGS2 | |
| SCHEMBL12997542 | 0.84 | PTGES (0.73) | ALOX5PTGS1PTGESALOX5APPTGS2 | |
| Methanesulfonamide SCHEMBL7843333 | 0.84 | ALOX5 (0.67) | ALOX5PTGS1PTGESALOX5APPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260451-A | Enzyme inhibitors | MERCKLE GMBH (DE) | 1993-11-09 | — | — | US | disclosed |