Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 4/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465025 | 0.92 | NR1H2 (0.48) | ALDH1A1HTTLMNASMN1; SMN2NR1H2 | |
| SCHEMBL9465535 | 0.86 | NR1H2 (0.61) | ALDH1A1HTTLMNANR1H2NR1H3 | |
| SCHEMBL17279699 | 0.73 | NR1H2 (0.71) | ALDH1A1HTTLMNASMN1; SMN2NR1H2 | |
| SCHEMBL27743131 | 0.72 | GAA (0.43) | ALDH1A1HTTSMN1; SMN2NR1H2NR1H3 | |
| SCHEMBL10743236 | 0.71 | PARP1 (0.63) | ALDH1A1HTTLMNAPARP1AR | |
| SCHEMBL14441714 | 0.71 | TGFBR1 (0.43) | IDO1GAA | |
| SCHEMBL12955388 | 0.70 | LMNA (0.72) | ALDH1A1HTTLMNASMN1; SMN2PARP1 | |
| SCHEMBL22307341 | 0.70 | NR1H2 (0.71) | ALDH1A1HTTLMNASMN1; SMN2NR1H2 | |
| SCHEMBL9464581 | 0.69 | MAPT (0.40) | ALDH1A1HTTLMNACYP2C9KDM4E | |
| SCHEMBL9464584 | 0.69 | ADRA1A (0.53) | ALDH1A1NR1H2NR1H3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |