Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464991 | 0.88 | ALDH1A1 (0.47) | TLR9SMN1; SMN2ALDH1A1TSHRKMT2A | |
| SCHEMBL9465107 | 0.86 | AVPR1B (0.53) | TLR9SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL9464969 | 0.84 | TSHR (0.46) | TLR9SMN1; SMN2ALDH1A1TSHRGAA | |
| SCHEMBL9465695 | 0.82 | MEN1 (0.49) | TLR9SMN1; SMN2ALDH1A1TSHRGAA | |
| SCHEMBL9465027 | 0.82 | MAPT (0.54) | TLR9SMN1; SMN2ALDH1A1TSHRGAA | |
| SCHEMBL9465413 | 0.80 | MEN1 (0.52) | TLR9SMN1; SMN2ALDH1A1TSHRGAA | |
| SCHEMBL9465008 | 0.78 | MAPT (0.47) | SMN1; SMN2ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL9464761 | 0.78 | TSHR (0.45) | TLR9SMN1; SMN2ALDH1A1TSHRGAA | |
| SCHEMBL9464710 | 0.78 | ALDH1A1 (0.45) | TLR9SMN1; SMN2ALDH1A1TSHRGAA | |
| SCHEMBL9464813 | 0.78 | AVPR1B (0.46) | SMN1; SMN2POLBMAPTRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |