Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464444 | 0.83 | ALPI (0.41) | PARP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL22072300 | 0.75 | LMNA (0.49) | PARP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL19483173 | 0.75 | PARP1 (0.47) | PARP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL28774206 | 0.74 | PARP1 (0.46) | PARP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL22073007 | 0.72 | MMP2 (0.46) | PARP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL27836650 | 0.72 | LMNA (0.52) | PARP1ALDH1A1HPGDHSD17B10MAPT | |
| Oxyquinoline SCHEMBL27982208 | 0.70 | METAP2 (0.66) | PARP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL6114228 | 0.68 | PARP1 (0.54) | PARP1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL869102 | 0.67 | KDM4E (0.54) | PARP1ALDH1A1HPGDHSD17B10MAPT | |
| Phenanthroline SCHEMBL28097109 | 0.67 | LMNA (0.73) | PARP1ALDH1A1MAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182398-A | α-Amino acid diamide and use thereof as cupric ion-transporting ionophore | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1993-01-26 | — | — | US | claimed |
| US-5182398-A | α-Amino acid diamide and use thereof as cupric ion-transporting ionophore | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1993-01-26 | — | — | US | disclosed |