Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.66 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CCKAR | P32238 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9466052 | 0.82 | PTGS2 (0.72) | PTGS2ALOX5RXRARXRBRXRG | |
| SCHEMBL9520508 | 0.81 | ALOX5 (0.83) | PTGS2ALOX5RXRARXRBRXRG | |
| SCHEMBL9465353 | 0.80 | PTGS2 (0.66) | PTGS2ALOX5RXRARXRBRXRG | |
| SCHEMBL9519062 | 0.80 | PTGS2 (0.81) | PTGS2ALOX5RXRARXRBRXRG | |
| Tepoxalin SCHEMBL75441 | 0.80 | PTGS2 (1.00) | PTGS2ALOX5RXRARXRBRXRG | |
| Tepoxalin SCHEMBL9519652 | 0.79 | PTGS2 (0.98) | PTGS2ALOX5RXRARXRBRXRG | |
| Formic Acid SCHEMBL9466099 | 0.76 | ALOX5 (0.66) | PTGS2ALOX5RXRARXRBRXRG | |
| Tepoxalin SCHEMBL28256087 | 0.74 | ALOX5 (0.87) | PTGS2ALOX5RXRARXRBRXRG | |
| SCHEMBL14445469 | 0.74 | ALOX5 (0.66) | PTGS2ALOX5RXRARXRBRXRG | |
| SCHEMBL9519454 | 0.73 | ALOX5 (0.79) | PTGS2ALOX5RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242940-A | Antiinflammatory agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-09-07 | — | — | US | claimed |
| US-5242940-A | Antiinflammatory agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-09-07 | — | — | US | disclosed |