Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465203 | 0.79 | MAOA (0.42) | MAOAMAOBCTSKALDH1A1MAPT | |
| SCHEMBL9465820 | 0.79 | CYP2D6 (0.44) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL21008631 | 0.77 | CTSK (0.43) | MAOACTSKCTSLCTSBALDH1A1 | |
| Bromide SCHEMBL11192117 | 0.77 | ALDH1A1 (0.39) | MAOAMAOBALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7362589 | 0.75 | ALDH1A1 (0.40) | MAOAMAOBALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL18869946 | 0.74 | ALDH1A1 (0.37) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL10337461 | 0.71 | MAOB (0.42) | MAOAMAOBCTSKCTSLALDH1A1 | |
| SCHEMBL20615333 | 0.70 | ALDH1A1 (0.40) | MAOAMAOBALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8967161 | 0.70 | MAOA (0.41) | MAOAMAOBALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7251291 | 0.70 | HPGD (0.37) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185460-A | Reacting hydrogen cyanide with desired mercaptan; recovering salt; intermediates for funcicides, herbicides, dyes, perfumes | NIPPON SODA CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| EP-0378707-B1 | AMINOACETONITRILE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0378707-A1 | AMINOACETONITRILE DERIVATIVES. | NIPPON SODA CO (JP) | 1990-07-25 | — | — | EP | disclosed |
| WO-1990000543-A1 | AMINOACETONITRILE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 1990-01-25 | — | — | WO | disclosed |