Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 4/20 | 0.45 |
| ▸ | FLT4 | P35916 | 4/20 | 0.45 |
| ▸ | KDR | P35968 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467928 | 0.84 | GPR17 (0.52) | CA12CA1CA2CA9TP53 | |
| SCHEMBL343103 | 0.84 | TP53 (0.52) | CA12CA1CA2CA9TP53 | |
| SCHEMBL9468048 | 0.82 | LMNA (0.58) | TP53PKMKMT2ARAB9ALMNA | |
| SCHEMBL9467743 | 0.82 | GAA (0.53) | CA12CA1CA2CA9TP53 | |
| SCHEMBL9967799 | 0.82 | BDKRB1 (0.62) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL9176593 | 0.81 | PTGS2 (0.64) | CA1CA2CA9TP53MEN1 | |
| SCHEMBL9176244 | 0.81 | HTT (0.56) | TP53MEN1KMT2AFLT1FLT4 | |
| SCHEMBL9468472 | 0.81 | TP53 (0.52) | CA12CA1CA2CA9TP53 | |
| SCHEMBL149860 | 0.79 | MEN1 (0.61) | CA1CA2TP53MEN1KMT2A | |
| SCHEMBL15624637 | 0.79 | FLT1 (0.64) | CA12CA1CA2CA9BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | claimed |
| EP-0365484-B1 | SULFAMOYL PHENYL UREAS | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | claimed |
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |