SCHEMBL9467928

SCHEMBL9467928

Cc1cccc(C(=O)NS(=O)(=O)c2ccc(NC(=O)N(C)C)cc2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR17 Q13304 1/20 0.52
RAB9A P51151 2/20 0.51
NPC1 O15118 1/20 0.51
TP53 P04637 1/20 0.51
BDKRB1 P46663 1/20 0.51
LMNA P02545 2/20 0.51
MAPT P10636 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
ALDH1A1 P00352 1/20 0.51
ALOX12 P18054 1/20 0.51
KAT6A Q92794 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
FLT1 P17948 1/20 0.49
FLT4 P35916 1/20 0.49
KDR P35968 1/20 0.49
KCNK3 O14649 1/20 0.48
KCNH2 Q12809 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9967799 0.86 BDKRB1 (0.62) BDKRB1LMNAMAPTSMN1; SMN2CA12
SCHEMBL7770076 0.84 RAB9A (0.56) GPR17RAB9ANPC1TP53LMNA
SCHEMBL9467720 0.84 CA12 (0.51) RAB9ANPC1TP53BDKRB1LMNA
SCHEMBL9467745 0.84 LMNA (0.54) GPR17RAB9ANPC1TP53BDKRB1
SCHEMBL8658192 0.83 ALDH1A1 (0.56) GPR17RAB9ANPC1TP53LMNA
SCHEMBL9179605 0.83 PTGS2 (0.64) TP53KAT6AFLT1FLT4KDR
SCHEMBL8655317 0.82 ALDH1A1 (0.56) GPR17RAB9ANPC1TP53LMNA
SCHEMBL9179058 0.80 KAT6A (0.74) LMNAMAPTSMN1; SMN2ALDH1A1KAT6A
SCHEMBL9467743 0.79 GAA (0.53) RAB9ANPC1TP53LMNAMAPT
SCHEMBL8658342 0.78 LMNA (0.60) RAB9ANPC1LMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5215570-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1993-06-01 US claimed
EP-0365484-B1 SULFAMOYL PHENYL UREAS CIBA-GEIGY AG (CH) 1993-01-07 EP claimed
US-5215570-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed