SCHEMBL9468014

SCHEMBL9468014

CNC(=O)Nc1cccc(S(=O)(=O)NC(=O)c2ccc(C)c(C)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.52
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
LMNA P02545 3/20 0.46
PTBP1 P26599 1/20 0.46
IDH1 O75874 2/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
ALDH1A1 P00352 2/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
POLB P06746 1/20 0.43
FBP1 P09467 1/20 0.43
CASP3 P42574 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
ITGB3 P05106 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL343103 0.86 TP53 (0.52) PKMMEN1KMT2ALMNACA12
SCHEMBL9468048 0.81 LMNA (0.58) PKMKMT2ALMNAHTT
SCHEMBL9176244 0.79 HTT (0.56) MEN1KMT2ALMNAALDH1A1HTT
SCHEMBL12049681 0.78 KMT2A (0.59) PKMMEN1KMT2ALMNAPTBP1
SCHEMBL9467745 0.76 LMNA (0.54) MEN1KMT2ALMNACA12CA1
SCHEMBL28119908 0.74 FLT1 (0.47) MEN1KMT2AALDH1A1HTT
SCHEMBL9468472 0.74 TP53 (0.52) PKMMEN1KMT2ALMNACA12
SCHEMBL9176593 0.74 PTGS2 (0.64) MEN1KMT2ACA1CA2CA9
SCHEMBL9484600 0.74 ALDH1A1 (0.56) MEN1KMT2ALMNAIDH1ALDH1A1
SCHEMBL9483282 0.74 MEN1 (0.56) MEN1KMT2ALMNACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5215570-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1993-06-01 US claimed
EP-0365484-B1 SULFAMOYL PHENYL UREAS CIBA-GEIGY AG (CH) 1993-01-07 EP claimed
US-5215570-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed