Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.51 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770076 | 0.90 | RAB9A (0.56) | LMNAGPR17TP53RAB9ANPC1 | |
| SCHEMBL9466896 | 0.88 | CA12 (0.56) | LMNATP53RAB9ACA12CA1 | |
| SCHEMBL28113465 | 0.85 | BDKRB1 (0.63) | LMNATP53CA12CA1CA2 | |
| SCHEMBL9467717 | 0.84 | HTT (0.57) | LMNAGPR17TP53RAB9AKAT6A | |
| SCHEMBL9468104 | 0.84 | CA1 (0.64) | LMNATP53RAB9ANPC1CA12 | |
| SCHEMBL9467928 | 0.84 | GPR17 (0.52) | LMNAGPR17TP53RAB9ANPC1 | |
| SCHEMBL8658192 | 0.84 | ALDH1A1 (0.56) | LMNAGPR17TP53RAB9ANPC1 | |
| SCHEMBL8658342 | 0.84 | LMNA (0.60) | LMNARAB9ANPC1RXFP1FLT1 | |
| SCHEMBL9179605 | 0.84 | PTGS2 (0.64) | TP53KAT6AFLT1FLT4KDR | |
| SCHEMBL343103 | 0.84 | TP53 (0.52) | LMNATP53RAB9ANPC1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | claimed |
| EP-0365484-B1 | SULFAMOYL PHENYL UREAS | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | claimed |
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |