SCHEMBL946830

SCHEMBL946830

c1ccc(Cc2ccc(SSc3ccc(Cc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.63
MAPT P10636 1/20 0.55
HPGD P15428 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MGLL Q99685 1/20 0.55
HSD17B10 Q99714 1/20 0.55
LTA4H P09960 3/20 0.48
IDH1 O75874 1/20 0.46
PLA2G10 O15496 1/20 0.45
PLA2G2A P14555 1/20 0.45
LMNA P02545 1/20 0.45
SLC22A2 O15244 1/20 0.43
ALDH1A1 P00352 1/20 0.42
MAPK1 P28482 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29090885 0.86 CALM1 (0.52) CALM1MAPTHPGDSMN1; SMN2MGLL
SCHEMBL534639 0.84 CALM1 (0.63) CALM1MAPTHPGDSMN1; SMN2LTA4H
SCHEMBL945034 0.84 HPGD (0.55) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL8094422 0.83 CALM1 (0.92) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL972712 0.83 CALM1 (0.92) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL10707308 0.82 CALM1 (0.60) CALM1MAPTHPGDSMN1; SMN2LTA4H
SCHEMBL27613417 0.80 SLC6A4 (0.58) CALM1MAPTLTA4HLMNAALDH1A1
SCHEMBL29106446 0.80 CALM1 (0.57) CALM1LTA4HIDH1PLA2G10PLA2G2A
Hydrochloric Acid SCHEMBL27978245 0.80 CALM1 (0.86) CALM1MAPTLTA4HIDH1PLA2G10
Diphenylmethane SCHEMBL4361124 0.80 CALM1 (1.00) CALM1MAPTHPGDHSD17B10LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987516-B2 Process for producing arylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2015-03-24 US disclosed
EP-2468722-B1 Process for producing arylsulfur halotetrafluorides UBE INDUSTRIES (JP) 2014-10-01 EP disclosed
EP-2468721-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2014-02-26 EP disclosed
EP-2468720-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-11-27 EP disclosed
EP-2468719-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-10-16 EP disclosed
EP-2137144-B1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES UBE INDUSTRIES (JP) 2013-07-31 EP disclosed
US-8399720-B2 Methods for producing fluorinated phenylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2013-03-19 US disclosed
EP-2468721-A1 Process for producing arylsulfur pentafluorides UBE Industries, Ltd. (JP) 2012-06-27 EP disclosed
EP-2468720-A1 Process for producing arylsulfur pentafluorides UBE Industries, Ltd. (JP) 2012-06-27 EP disclosed
EP-2468719-A1 Process for producing arylsulfur pentafluorides UBE Industries, Ltd. (JP) 2012-06-27 EP disclosed
US-20110004022-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2011-01-06 US disclosed
US-7851646-B2 formed by reacting aryl sulfur compound with halogen and fluoro salt to form arylsulfur halotetrafluoride which is reacted with fluoride source to form target arylsulfur pentafluoride; for production of fungicides, herbicides, and insecticides IM&T RESEARCH, INC. (US) 2010-12-14 US disclosed
US-7820864-B2 2,3,4,5,6-pentafluorophenylsulfur pentafluoride; as intermediates for introduce sulfur pentafluoride groups into various commercial organic molecules; liquid crystals, fungicides, herbicides, and insecticides IM&T RESEARCH, INC. (US) 2010-10-26 US disclosed
US-20100130790-A1 Methods for Producing Fluorinated Phenylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-05-27 US disclosed
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-03-25 US disclosed
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-02-04 US disclosed
WO-2010014665-A1 METHODS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T RESEARCH, INC. (US) 2010-02-04 WO disclosed
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2009-11-19 US disclosed
US-7592491-B2 Process for producing arylsulfur pentafluorides IM&T RESEARCH, INC. (US) 2009-09-22 US disclosed
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T RESEARCH, INC. (US) 2008-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA CALM1 3478/4885MAPT 3764/4885HPGD 4312/4885
US-20100130790-A1 Methods for Producing Fluorinated Phenylsulfur Pentafluorides BRPF1, SFXN3, SLFN12 CALM1 4704/4885MAPT 3665/4885HPGD 4371/4885
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA CALM1 3478/4885MAPT 3764/4885HPGD 4312/4885
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES PFAS, MPST, ARSA CALM1 3478/4885MAPT 3764/4885HPGD 4312/4885
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA CALM1 3478/4885MAPT 3764/4885HPGD 4312/4885
US-20110004022-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA CALM1 3478/4885MAPT 3764/4885HPGD 4312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.