Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468974 | 0.79 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9469700 | 0.76 | ALDH1A1 (0.51) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8947235 | 0.74 | ALDH1A1 (0.59) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9469451 | 0.71 | ALDH1A1 (0.62) | ALDH1A1KMT2AHPGDHSD11B1KDM4C | |
| SCHEMBL9689917 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KMT2AHPGDRAB9AHSD11B1 | |
| SCHEMBL9568847 | 0.71 | ALDH1A1 (0.48) | MAPTALDH1A1KMT2AHPGDRAB9A | |
| SCHEMBL5966693 | 0.71 | ALDH1A1 (0.74) | ALDH1A1HPGDHSD11B1KDM4CTSHR | |
| SCHEMBL2521660 | 0.71 | MAPT (0.65) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8947137 | 0.70 | ALDH1A1 (0.53) | MAPTALDH1A1HPGDSMN1; SMN2HSD11B1 | |
| SCHEMBL5966725 | 0.70 | ALDH1A1 (0.68) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4244070-A | — | — | None | — | — | JP | disclosed |
| US-5252592-A | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1993-10-12 | — | — | US | disclosed |
| JP-H04244070-A | TETRAZOLE ACETIC ACID DERIVATIVE HAVING ALDOSE REDUCTASE INHIBITORY ACTIVITY | WAKAMOTO PHARMACEUT CO LTD | 1992-09-01 | — | — | JP | disclosed |