Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599636 | 0.81 | TDP1 (0.41) | CCR2ALDH1A1LMNACHRNA1CHRNG | |
| SCHEMBL9354728 | 0.80 | CA1 (0.44) | LMNAHSD11B1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL10718399 | 0.78 | PTGS2 (0.35) | CCR2ALDH1A1LMNASRD5A2SMN1; SMN2 | |
| SCHEMBL206382 | 0.70 | ALDH1A1 (0.48) | CCR2ALDH1A1LMNASRD5A2SMN1; SMN2 | |
| SCHEMBL10780144 | 0.69 | ALDH1A1 (0.37) | CCR2ALDH1A1LMNACHRNB2SLC6A2 | |
| SCHEMBL29031878 | 0.67 | ALDH1A1 (0.44) | CCR2ALDH1A1LMNASRD5A2SMN1; SMN2 | |
| SCHEMBL5472097 | 0.67 | CCR2 (0.42) | CCR2ALDH1A1LMNASRD5A2SMN1; SMN2 | |
| SCHEMBL9852819 | 0.67 | L3MBTL1 (0.42) | CCR2ALDH1A1LMNASRD5A2SMN1; SMN2 | |
| SCHEMBL351393 | 0.65 | AKR1C1 (0.55) | ALDH1A1LMNASMN1; SMN2HSD11B1AKR1C3 | |
| SCHEMBL9257647 | 0.65 | PTGS2 (0.38) | ALDH1A1LMNAHSD11B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5244803-A | Stereoselective hydrolysis by microorganism in culture | TANABE SEIYAKU CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |