Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470747 | 0.79 | ATM (0.47) | RAB9AKDM4ENPC1ALDH1A1POLB | |
| SCHEMBL7371232 | 0.77 | MGAM (0.76) | TOP2ATOP2BCHEK2MGAMPDE4D | |
| SCHEMBL9682938 | 0.76 | TOP2A (0.51) | TOP2ATOP2BCHEK2MGAMPDE4D | |
| Bromide SCHEMBL7374451 | 0.76 | MGAM (0.73) | TOP2ATOP2BCHEK2MGAMPDE4D | |
| SCHEMBL9470246 | 0.75 | MAP2K1 (0.47) | ALDH1A1HPGD | |
| SCHEMBL9470575 | 0.74 | LTA4H (0.44) | CHEK2RAB9AALDH1A1POLBHPGD | |
| SCHEMBL31629977 | 0.72 | MGAM (0.78) | TOP2ATOP2BCHEK2MGAMPDE4D | |
| SCHEMBL28286128 | 0.72 | MGAM (0.78) | TOP2ATOP2BCHEK2MGAMPDE4D | |
| SCHEMBL30875867 | 0.71 | RAB9A (0.62) | TOP2ATOP2BCHEK2MGAMPDE4D | |
| SCHEMBL3565655 | 0.69 | CHEK2 (0.69) | TOP2ATOP2BCHEK2MGAMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246951-A | Nonsteroidal antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1993-09-21 | — | — | US | disclosed |