Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FABP6 | P51161 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470203 | 0.85 | CDC25B (0.54) | ATMALDH1A1POLBKDM4EGLA | |
| SCHEMBL9470575 | 0.85 | LTA4H (0.44) | L3MBTL1ALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9470246 | 0.83 | MAP2K1 (0.47) | ALDH1A1HPGD | |
| SCHEMBL5465671 | 0.81 | TDP1 (0.50) | TDP1L3MBTL1ALDH1A1POLBSRD5A2 | |
| SCHEMBL9469729 | 0.79 | TOP2A (0.51) | ALDH1A1RAB9ASMN1; SMN2HPGDABL1 | |
| SCHEMBL9469937 | 0.76 | ALDH1A1 (0.44) | TDP1ALDH1A1RAB9AHPGDHTT | |
| SCHEMBL24576213 | 0.73 | MEN1 (0.64) | ATMTDP1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL11947173 | 0.73 | MEN1 (0.60) | ATMTDP1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL9470340 | 0.70 | FEN1 (0.43) | ALDH1A1SMN1; SMN2POLBKDM4EMEN1 | |
| SCHEMBL5727283 | 0.70 | ESR1 (0.52) | ATMTDP1L3MBTL1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246951-A | Nonsteroidal antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1993-09-21 | — | — | US | claimed |
| EP-0487423-A1 | Benzoselenazolinone derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-05-27 | — | — | EP | claimed |
| US-5246951-A | Nonsteroidal antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1993-09-21 | — | — | US | disclosed |
| EP-0487423-A1 | Benzoselenazolinone derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-05-27 | — | — | EP | disclosed |