Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668108 | 0.87 | TBXAS1 (0.44) | CNR2CNR1LMNAMAPTALDH1A1 | |
| SCHEMBL15759095 | 0.84 | LMNA (0.46) | CNR2CNR1LMNAMAPTALDH1A1 | |
| SCHEMBL20604920 | 0.83 | KDM4E (0.47) | CNR2CNR1LMNAMAPTKDM4E | |
| SCHEMBL23175314 | 0.78 | GPR84 (0.61) | LMNAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL29623198 | 0.78 | GPR84 (0.61) | LMNAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL18509694 | 0.78 | LMNA (0.49) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL28566679 | 0.76 | ADRB2 (0.41) | LMNAMAPTKDM4ENQO2MTNR1A | |
| SCHEMBL18029130 | 0.75 | MAPT (0.48) | LMNAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL7385651 | 0.75 | KMT2A (0.41) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2381934 | 0.74 | HTR6 (0.47) | LMNAMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192770-A | Antiemetic, anxiolytic, cognition activator | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |