Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21845015 | 0.80 | KDM4E (0.48) | KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL28520089 | 0.80 | BBOX1 (0.31) | — | |
| SCHEMBL13205118 | 0.78 | PLA2G2A (0.36) | ALDH1A1 | |
| SCHEMBL24109495 | 0.78 | ALDH1A1 (0.43) | KEAP1NFE2L2KMT2AMTNR1AHSD17B10 | |
| SCHEMBL19411349 | 0.78 | — | — | |
| SCHEMBL12587309 | 0.77 | EPHX1 (0.50) | KMT2AHSD17B10EPHX1ALDH1A1 | |
| SCHEMBL9011086 | 0.77 | TDP1 (0.40) | ALDH1A1 | |
| SCHEMBL10018100 | 0.75 | EPHX1 (0.44) | KMT2AMTNR1AMTNR1BEPHX1ALDH1A1 | |
| SCHEMBL8549199 | 0.75 | KEAP1 (0.37) | KEAP1NFE2L2KMT2AMTNR1AHSD17B10 | |
| SCHEMBL13853553 | 0.75 | LMNA (0.48) | KEAP1NFE2L2KMT2AMTNR1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270412-A | Dispersion polymers which contain urea groups and are based on ethylenically unsaturated monomers, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-14 | — | — | US | disclosed |
| US-5045616-A | Disperson polymers which contain urea groups and are based on ethylenically unsaturated monomers, process for their preparation and their use | HOECHST AG (DE) | 1991-09-03 | — | — | US | disclosed |