Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MASP2 | O00187 | 1/20 | 0.49 |
| ▸ | CFD | P00746 | 1/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9474718 | 0.86 | ALDH1A1 (0.62) | ALDH1A1KDM4EPOLBHCAR2NPC1 | |
| SCHEMBL8485409 | 0.86 | ALDH1A1 (0.63) | ALDH1A1KDM4EPOLBABCC1NPC1 | |
| SCHEMBL9475280 | 0.74 | POLB (0.54) | ALDH1A1KDM4EPOLBGAAHPGD | |
| SCHEMBL9474583 | 0.72 | POLB (0.58) | ALDH1A1KDM4EPOLBNPC1TP53 | |
| SCHEMBL5696444 | 0.71 | ALDH1A1 (0.68) | ALDH1A1KDM4EPOLBHCAR2L3MBTL1 | |
| SCHEMBL14340794 | 0.71 | ALDH1A1 (0.63) | ALDH1A1KDM4EHCAR2L3MBTL1CFD | |
| SCHEMBL2779110 | 0.71 | MEN1 (0.65) | ALDH1A1KDM4EPOLBNPC1RAB9A | |
| SCHEMBL2779107 | 0.71 | MEN1 (0.65) | ALDH1A1KDM4EPOLBNPC1RAB9A | |
| SCHEMBL11571477 | 0.71 | L3MBTL1 (0.54) | POLBL3MBTL1KMT2A | |
| SCHEMBL4040223 | 0.70 | ALDH1A1 (0.82) | ALDH1A1KDM4EPOLBABCC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217961-A | High carcinostatic activity; inhibiting KB-cell growth | MECT CORPORATION (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0376166-A1 | Condensed quinoline system compound and process of preparation thereof | MECT CORPORATION (JP) | 1990-07-04 | — | — | EP | disclosed |