Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485409 | 0.77 | ALDH1A1 (0.63) | POLBALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL10364156 | 0.77 | CFD (0.62) | POLBALDH1A1KDM4EALOX12SMN1; SMN2 | |
| SCHEMBL6929631 | 0.76 | NPC1 (0.63) | POLBALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL9474583 | 0.75 | POLB (0.58) | POLBALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL10362773 | 0.75 | KMT2A (0.53) | POLBALDH1A1KDM4EALOX12CYP1A2 | |
| SCHEMBL950942 | 0.75 | POLB (0.62) | POLBALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL11665956 | 0.74 | KDM4E (0.78) | POLBALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL9958891 | 0.74 | POLB (0.60) | POLBALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL9473974 | 0.74 | ALDH1A1 (0.57) | POLBALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL13541545 | 0.73 | HPGD (0.70) | POLBALDH1A1ALOX12CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217961-A | High carcinostatic activity; inhibiting KB-cell growth | MECT CORPORATION (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0376166-A1 | Condensed quinoline system compound and process of preparation thereof | MECT CORPORATION (JP) | 1990-07-04 | — | — | EP | disclosed |