SCHEMBL9474265

SCHEMBL9474265

CCSc1ccc(Oc2ccc(CN)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ST14 Q9Y5Y6 3/20 0.57
SLC6A4 P31645 9/20 0.53
MAOA P21397 2/20 0.53
ALDH1A1 P00352 1/20 0.42
MAOB P27338 2/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15485754 0.88 SLC6A4 (0.64) SLC6A4MAOAMAOB
SCHEMBL9501765 0.81 SLC6A4 (0.44) ST14SLC6A4MAOAALDH1A1MAOB
SCHEMBL920206 0.81 ST14 (0.61) ST14SLC6A4MAOAMAOBKEAP1
SCHEMBL4209153 0.79 ST14 (0.85) ST14MAOBKEAP1NFE2L2
SCHEMBL13969406 0.79 LTA4H (0.55) MAOAALDH1A1
SCHEMBL18892562 0.79 ALDH1A1 (0.46) SLC6A4MAOAALDH1A1MAOB
SCHEMBL920620 0.78 ST14 (0.68) ST14MAOBKEAP1NFE2L2
SCHEMBL22068903 0.77 ALDH1A1 (0.44) SLC6A4MAOAALDH1A1
SCHEMBL920089 0.76 ST14 (0.50) ST14ALDH1A1MAOB
SCHEMBL920213 0.75 ST14 (0.63) ST14MAOBKEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5264448-A Thioamides, oxazole ring, insecticides, miticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-23 US disclosed
EP-0394043-A1 An amide compound and its production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-24 EP disclosed