SCHEMBL4209153

SCHEMBL4209153

NCc1ccc(Oc2ccc(CN)cc2)cc1

nearest known ligand 0.85

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ST14 Q9Y5Y6 3/20 0.85
HRH3 Q9Y5N1 1/20 0.55
LOXL2 Q9Y4K0 2/20 0.52
MAOB P27338 6/20 0.50
ABAT P80404 1/20 0.50
MMP2 P08253 2/20 0.49
MMP9 P14780 2/20 0.49
MMP8 P22894 2/20 0.49
MMP14 P50281 2/20 0.49
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28006451 0.92 ST14 (0.74) ST14HRH3LOXL2MAOBMMP2
SCHEMBL12634637 0.90 LOXL2 (0.71) ST14LOXL2MAOB
SCHEMBL121432 0.90 ST14 (0.71) ST14LOXL2MAOB
SCHEMBL6158673 0.88 ST14 (0.68) ST14HRH3MAOBMMP2MMP9
SCHEMBL920324 0.88 ST14 (0.68) ST14MAOB
SCHEMBL6391600 0.88 ABAT (0.73) ST14ABAT
Hydrochloric Acid SCHEMBL922977 0.88 ST14 (0.68) ST14LOXL2MAOB
SCHEMBL919783 0.88 LOXL2 (0.73) ST14LOXL2MAOB
SCHEMBL921428 0.88 ST14 (0.68) ST14HRH3MAOB
SCHEMBL920620 0.88 ST14 (0.68) ST14HRH3LOXL2MAOBMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2668968-B1 Polymeric ascorbic acid devices for tissue regeneration COVIDIEN LP (US) 2019-08-14 EP claimed
CN-107787183-A Fertilizer and agrochemical formulations 三井化学AGRO株式会社 2018-03-09 CN claimed
EP-3831806-B1 DIISOCYANATE COMPOSITION FOR OPTICAL LENS AND PREPARATION METHOD THEREOF SK PUCORE CO LTD (KR) 2024-07-10 EP disclosed
US-11987541-B2 Method of preparing diisocyanate composition SK PUCORE CO., LTD. (KR) 2024-05-21 US disclosed
US-11964931-B2 Method of preparing diisocyanate composition and optical lens SK PUCORE CO., LTD. (KR) 2024-04-23 US disclosed
US-11932591-B2 Method of preparing diisocyanate composition and optical lens SKC CO., LTD. (KR) 2024-03-19 US disclosed
US-20230357136-A1 DIAMINE COMPOSITION, AND METHOD OF PREPARING DIISOCYANATE COMPOSITION SK PUCORE CO., LTD. (KR) 2023-11-09 US disclosed
US-11760719-B2 Diamine composition, and method of preparing diisocyanate composition SKC CO., LTD. (KR) 2023-09-19 US disclosed
US-11731936-B2 Diisocyanate composition, preparation method thereof and optical material using same SKC CO., LTD. (KR) 2023-08-22 US disclosed
US-11702384-B2 Diisocyanate composition for optical lens and preparation method thereof SKC CO., LTD. (KR) 2023-07-18 US disclosed
US-11634383-B2 Method of preparing diisocyanate composition SKC CO., LTD. (KR) 2023-04-25 US disclosed
EP-1296540-A1 DISPLAY TORAY INDUSTRIES, INC. (JP) 2003-03-26 EP disclosed
US-20020162998-A1 Display TORAY INDUSTRIES, INC. (JP) 2002-11-07 US disclosed
US-6090525-A PHOTOSENSITIVE POLYIMIDE COATING AGENT COMPOSITION WITH BOTH GOOD VISCOSITY STABILITY AT ROOM TEMPERATURE WITH LAPSE OF TIME AND GOOD PHOTOSENSITIVE PERFORMANCE TORAY INDUSTRIES, INC. (JP) 2000-07-18 US disclosed
CN-1201061-A Chemical-ray sensitive polymer composition TORAY CO LTD (JP) 1998-12-09 CN disclosed
EP-0369219-B1 Light-sensitive compounds, preparation of a light-sensitive mixture therewith and a recording material HOECHST AG (DE) 1995-01-04 EP disclosed
CN-1077841-A A kind of new plant growth regulator composition and using method thereof TROPICANA PROD INC (US) 1993-11-03 CN disclosed
US-5114816-A RADIATION-SENSITIVE COMPOUNDS, RADIATION-SENSITIVE MIXTURE PREPARED THEREWITH AND COPYING MATERIAL HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-19 US disclosed
US-4847395-A MOLDING MATERIALS, ETHERSULFONAMIDES KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-07-11 US disclosed
EP-0265753-A1 Novel glycidyl compounds and process for preparation thereof KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-05-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11987541-B2 Method of preparing diisocyanate composition INCENP, CENPE, SMO ST14 1520/4885HRH3 1031/4885LOXL2 4783/4885
US-11964931-B2 Method of preparing diisocyanate composition and optical lens CRYAA, GCG, UACA ST14 1393/4885HRH3 648/4885LOXL2 4260/4885
US-20230357136-A1 DIAMINE COMPOSITION, AND METHOD OF PREPARING DIISOCYANATE COMPOSITION INCENP, CENPE, BRI3BP ST14 2047/4885HRH3 2562/4885LOXL2 4503/4885
US-11634383-B2 Method of preparing diisocyanate composition INCENP, CENPE, CRYAA ST14 1034/4885HRH3 3719/4885LOXL2 4568/4885
US-11932591-B2 Method of preparing diisocyanate composition and optical lens CRYAA, GCG, AGT ST14 1539/4885HRH3 1178/4885LOXL2 4087/4885
US-11731936-B2 Diisocyanate composition, preparation method thereof and optical material using same SMO, GCG, INCENP ST14 1918/4885HRH3 744/4885LOXL2 3558/4885
US-11760719-B2 Diamine composition, and method of preparing diisocyanate composition UACA, CENPE, CD79B ST14 2941/4885HRH3 1715/4885LOXL2 4473/4885
US-11702384-B2 Diisocyanate composition for optical lens and preparation method thereof INCENP, CRYAA, MYOC ST14 1809/4885HRH3 2446/4885LOXL2 2316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.