SCHEMBL920206

SCHEMBL920206

CSc1ccc(Oc2ccc(CN)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ST14 Q9Y5Y6 3/20 0.61
SLC6A4 P31645 6/20 0.50
MAOA P21397 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
MAOB P27338 2/20 0.42
AOC3 Q16853 1/20 0.42
HTR2A P28223 1/20 0.42
KCNH2 Q12809 1/20 0.42
GAA P10253 1/20 0.42
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
CYP1A1 P04798 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP1B1 Q16678 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2092148 0.87 SLC6A4 (0.61) SLC6A4MAOASLC6A2SLC6A3CYP1A2
SCHEMBL920834 0.86 ST14 (0.50) ST14SLC6A4MAOBHTR2AKCNH2
Bromide SCHEMBL31206810 0.85 SLC6A4 (0.59) SLC6A4MAOASLC6A2SLC6A3CYP1A2
Hydrochloric Acid SCHEMBL9219902 0.85 SLC6A4 (0.59) SLC6A4MAOASLC6A2SLC6A3CYP1A2
SCHEMBL2774995 0.82 CYP1A1 (0.52) SLC6A4SLC6A2SLC6A3MAOBAOC3
SCHEMBL4209153 0.82 ST14 (0.85) ST14MAOBKEAP1NFE2L2
SCHEMBL16316305 0.82 SMN1; SMN2 (0.46) SLC6A4MAOASLC6A2SLC6A3HTR2A
SCHEMBL9474265 0.81 ST14 (0.57) ST14SLC6A4MAOAMAOBKEAP1
SCHEMBL920995 0.80 ST14 (0.47) ST14SLC6A4MAOASLC6A2SLC6A3
SCHEMBL9474042 0.80 LTA4H (0.59) SLC6A4MAOASLC6A2SLC6A3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111848592-B 4-aminofuran-2 (5H) ketone compound, preparation method and application thereof 东莞市东阳光农药研发有限公司 2023-10-17 CN disclosed
CN-111848592-A 4-aminofuran-2 (5H) ketone compound, preparation method and application thereof 东莞市东阳光农药研发有限公司 2020-10-30 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
US-5264448-A Thioamides, oxazole ring, insecticides, miticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-23 US disclosed
US-5206259-A Insecticides, acaricides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-04-27 US disclosed
EP-0394043-A1 An amide compound and its production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-24 EP disclosed
EP-0378487-A1 Stabilizer web with a heating insert for soilless culture and for a container platform in a protected culture NOTEX S.A. (FR) 1990-07-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ST14 708/4885SLC6A4 2590/4885MAOA 3447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.