Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1391150 | 0.88 | SLC6A4 (0.53) | SLC6A4MAOAALDH1A1MAOBRAB9A | |
| SCHEMBL9503139 | 0.86 | MAOA (0.47) | MAOAALDH1A1APPSMN1; SMN2TTR | |
| SCHEMBL9505718 | 0.84 | TTR (0.43) | SLC6A4MAOAALDH1A1SMN1; SMN2TTR | |
| SCHEMBL9503534 | 0.83 | MAOA (0.50) | MAOAALDH1A1MAOBRAB9ALTA4H | |
| SCHEMBL10731219 | 0.82 | ALDH1A1 (0.40) | MAOAALDH1A1APPSMN1; SMN2TTR | |
| SCHEMBL10731318 | 0.82 | ALDH1A1 (0.40) | SLC6A4MAOAALDH1A1APPSMN1; SMN2 | |
| SCHEMBL9503547 | 0.82 | MAOA (0.45) | MAOAALDH1A1SMN1; SMN2MAOBRAB9A | |
| SCHEMBL9474265 | 0.81 | ST14 (0.57) | SLC6A4MAOAALDH1A1MAOBST14 | |
| SCHEMBL9502046 | 0.81 | SLC6A4 (0.43) | SLC6A4MAOARAB9A | |
| SCHEMBL9503477 | 0.81 | ALDH1A1 (0.39) | SLC6A4MAOAALDH1A1APPTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186190-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0132606-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4663339-A | Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-05 | — | — | US | disclosed |
| US-4612323-A | Insecticidal and acaricidal derivatives of 1-benzylbenzimidazole | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0186190-A2 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0132606-A1 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-02-13 | — | — | EP | disclosed |