SCHEMBL9474691

SCHEMBL9474691

O=C1CC[C@@H](C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N2CCC[C@H]2C(=O)O)N1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TRHR P34981 6/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11815435 0.97 TRHR (0.57) TRHR
SCHEMBL11820778 0.97 TRHR (0.57) TRHR
Protirelin SCHEMBL11669085 0.92 TRHR (0.68) TRHR
Protirelin SCHEMBL8364920 0.92 TRHR (0.71) TRHR
Protirelin SCHEMBL14280929 0.92 TRHR (0.71) TRHR
Protirelin SCHEMBL20659679 0.92 TRHR (0.71) TRHR
Protirelin SCHEMBL11798811 0.92 TRHR (0.71) TRHR
Protirelin SCHEMBL2182035 0.92 TRHR (0.71) TRHR
SCHEMBL1369554 0.91 TRHR (0.63) TRHR
SCHEMBL27209499 0.91 TRHR (0.56) TRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5225529-A Central nervous system disorders such as Alzheimer*s disease FARMHISPANIA S.A. (ES) 1993-07-06 — — US claimed
EP-0381070-A1 Synthetic amphiphilic glycoconjugates for neurological use FARMHISPANIA S.A. (ES) 1990-08-08 — — EP claimed
WO-2026089754-A1 COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF THERAPEUTIC PEPTIDES Finitus, LLC (US) 2026-04-30 — — WO disclosed
WO-2026089752-A1 COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES Finitus, LLC (US) 2026-04-30 — — WO disclosed
US-20260108467-A1 COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES FINITUS LLC (US) 2026-04-23 — — US disclosed
US-20260108583-A1 COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF THERAPEUTIC PEPTIDES FINITUS LLC (US) 2026-04-23 — — US disclosed
CN-114516898-A Preparation method and application of thyrotropin releasing hormone 上海丽珠制药有限公司 2022-05-20 — — CN disclosed
US-5225529-A Central nervous system disorders such as Alzheimer*s disease FARMHISPANIA S.A. (ES) 1993-07-06 — — US disclosed
EP-0381070-A1 Synthetic amphiphilic glycoconjugates for neurological use FARMHISPANIA S.A. (ES) 1990-08-08 — — EP disclosed
US-4297346-A PSYCHOACTIVE DRUGS BONDED TO NEUROPEPTIDES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 1981-10-27 — — US disclosed
US-4066635-A ANTIDEPRESSANTS HOFFMANN-LA ROCHE INC. (US) 1978-01-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108583-A1 COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF THERAPEUTIC PEPTIDES MUC1, VIP, LGALS4 TRHR 280/4885
US-20260108467-A1 COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES FGF23, FIBP, PTMS TRHR 1002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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