Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | PPOX | P50336 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9474758 | 0.89 | MAPT (0.46) | ALDH1A1HTTPKMNPC1RAB9A | |
| SCHEMBL10471816 | 0.84 | PKM (0.42) | ALDH1A1HTTPKMNPC1RAB9A | |
| SCHEMBL1836695 | 0.81 | PKM (0.41) | ALDH1A1HTTPKMNPC1RAB9A | |
| SCHEMBL3385215 | 0.81 | TGFBR1 (0.38) | ALDH1A1HTTPKMNPC1RAB9A | |
| SCHEMBL10472809 | 0.79 | SIRT6 (0.42) | ALDH1A1HTTMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9133070 | 0.78 | PKM (0.53) | ALDH1A1HTTPKMNPC1RAB9A | |
| SCHEMBL9474036 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HTTMAPTSMN1; SMN2MEN1 | |
| SCHEMBL1153683 | 0.75 | PKM (0.46) | ALDH1A1PKMNPC1RAB9AMAPT | |
| SCHEMBL5223849 | 0.75 | MAPT (0.43) | ALDH1A1HTTPKMNPC1MAPT | |
| SCHEMBL9474164 | 0.75 | PKM (0.45) | ALDH1A1PKMNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190574-A | HERBICIDAL PYRAZOLYLOXY AND PYRAZOLYLAMINO-BENZOTRIAZOLES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-02 | — | — | US | disclosed |