SCHEMBL9475407

SCHEMBL9475407

CCNC(=O)OCOC(=O)NCC

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.48
CHRNB4 P30926 1/20 0.48
CHRNA3 P32297 1/20 0.48
CHRNA4 P43681 1/20 0.48
ALDH1A1 P00352 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
EPHX1 P07099 1/20 0.43
ACHE P22303 8/20 0.43
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12035543 0.89 ALOX15 (0.46) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL15113723 0.87 CHRNB2 (0.49) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL13007370 0.85 CHRNB2 (0.43) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL149187 0.83
SCHEMBL16674069 0.83 ACHE (0.60) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL10822205 0.83 TSHR (0.46) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL11544171 0.83 THRB (0.44) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL9246745 0.82 CHRNB2 (0.41) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL6251476 0.82 ALDH1A1 (0.40) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL19810523 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5220061-A Slowyly mixing n,n dialkyl-n-phenylurea and methylene bis/ alkyl carbamate/ with acid catalyst; heating ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1993-06-15 US claimed
US-5206412-A Reacting alkylphenylcarbamate with methylene bis(alkyl carbamate); acid catlayst ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1993-04-27 US claimed
US-8168729-B2 Thermosetting resin composition DIC CORPORATION (JP) 2012-05-01 US disclosed
US-20090192273-A1 THERMOSETTING RESIN COMPOSITION DIC CORPORATION (JP) 2009-07-30 US disclosed
US-5220061-A Slowyly mixing n,n dialkyl-n-phenylurea and methylene bis/ alkyl carbamate/ with acid catalyst; heating ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1993-06-15 US disclosed
US-5206412-A Reacting alkylphenylcarbamate with methylene bis(alkyl carbamate); acid catlayst ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1993-04-27 US disclosed
US-5126476-A Reaction of aromatic compound with alkylenebis(alkyl carbamate) in presence of acid catalyst and polar aprotic solv ent ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1992-06-30 US disclosed