Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 2/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9476499 | 0.81 | ADRA1A (0.47) | KDM4EALDH1A1SMN1; SMN2CTSDBACE1 | |
| SCHEMBL9475729 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1SMN1; SMN2ADRA1AMETAP1 | |
| SCHEMBL9476028 | 0.80 | KDM4C (0.47) | KDM4EPOLB | |
| SCHEMBL9476447 | 0.79 | CA9 (0.43) | CTSDBACE1 | |
| SCHEMBL9476629 | 0.79 | CHEK2 (0.42) | KDM4EALDH1A1CTSDBACE1MAPT | |
| SCHEMBL9475857 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1SMN1; SMN2ADRA1ANPSR1 | |
| SCHEMBL9476040 | 0.78 | CBFB (0.40) | KDM4EALDH1A1SMN1; SMN2CTSDBACE1 | |
| SCHEMBL9483632 | 0.78 | GABRA3 (0.46) | KDM4EALDH1A1SMN1; SMN2CTSDBACE1 | |
| SCHEMBL9475451 | 0.78 | CBFB (0.40) | KDM4EALDH1A1SMN1; SMN2NPSR1NPC1 | |
| SCHEMBL9475150 | 0.78 | METAP2 (0.40) | KDM4EALDH1A1SMN1; SMN2NPSR1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0477789-A1 | 1,3-Benzoxazine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |