Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475647 | 0.82 | CBFB (0.43) | CBFBCHRM1GRM5KMT2AMEN1 | |
| SCHEMBL9476499 | 0.81 | ADRA1A (0.47) | NPC1RAB9ASMN1; SMN2CHRM1GRM5 | |
| SCHEMBL9475729 | 0.80 | KDM4E (0.39) | NPC1RAB9AMAPK1SMN1; SMN2CHRM1 | |
| SCHEMBL9372830 | 0.79 | DRD2 (0.39) | CBFBMAPK1SMN1; SMN2GRM5KMT2A | |
| SCHEMBL27344045 | 0.79 | TP53 (0.33) | NPC1RAB9AMAPTATMKDM4E | |
| SCHEMBL9477563 | 0.78 | SLC40A1 (0.38) | RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL9475857 | 0.78 | KDM4E (0.36) | NPC1RAB9AMAPK1SMN1; SMN2CHRM1 | |
| SCHEMBL9523928 | 0.78 | CBFB (0.40) | CBFBNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL9483632 | 0.78 | GABRA3 (0.46) | NPC1RAB9ASMN1; SMN2CHRM1ALDH1A1 | |
| SCHEMBL9475150 | 0.78 | METAP2 (0.40) | SMN1; SMN2GRM5ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060467-A | 1,3-benzoxazine derivatives, its production method and purposes | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-04-22 | — | — | CN | claimed |
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| CN-1060467-A | 1,3-benzoxazine derivatives, its production method and purposes | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-04-22 | — | — | CN | disclosed |
| EP-0477789-A1 | 1,3-Benzoxazine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |